|Catalog No.：||GT0089519||Formula：||C39H44N2O7||Molecular Weight：||652.77|
|Physical Description：||Powder||Type of Compound：||Alkaloids|
|Download：||Similar structural：||Comparison (Web)|
Honorific customer, once receiving your message, we will give you the reply as soon as possible!
|Source:||The roots of Thalictrum podocarpum.|
|Biological Activity or Inhibitors:||1. Hernandezine, a novel AMPK activator, can inhibit LPS-induced TNFα expression/production in human macrophage cells (THP-1 and U937 lines).
2. Hernandezine is a potent and selective reversing agent for ABCB1-mediated MDR in cancer cells.
3. Hernandezine inhibits calcium-depletion stimulated calcium entry in human and bovine endothelial cells.
4. Hernandezine induces autophagic cell death in drug-resistant cancers.
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8℃(35.6-46.4℉)).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|